About
The core technology in RSI products was invented from many years of R&D by RSI founders Debra Wawro Weidanz, CEO (Former Co-Founder and CEO of Abexxa Biologics, Inc. acquired by Boehringer Ingelheim) and Dr. Robert Magnusson, CTO (Texas Instruments Distinguished University Chair in Nanoelectronics). Our core team includes Dr. Jon Weidanz (Assay Development and Applications) who is a pioneer in peptide/HLA based immunotherapy development (Former Co-Founder and CSO of Abexxa Biologics, Inc.).
Selected references
- Schaap G., Ghaffari S., Middelburg J., Sluijter M., Griffioen L., Schoufour T.A.W., Wijdeven R.H.M., Neefjes J., Arens R., Weidanz J., van Hall T. (2026). The murine MHC-E molecule Qa-1b is surface displayed in a peptide-free conformation in homeostasis. Frontiers in Immunology, 17:1743362. https://doi.org/10.3389/fimmu.2026.1743362
- Watters C.R., Ghaffari S., Wilder C., Donkor M., Gimlin S., Oter G., et al. (2024). HLA-E interacts with VISTA in a peptide-dependent manner. Journal for Immunotherapy of Cancer, 12. https://doi.org/10.1136/jitc-2024-SITC2024.0845
- Magnusson R., Ko Y.H., Lee K.J., Simlan F.A., Bootpakdeetam P., Chen R., Wawro Weidanz D., Gimlin S., Ghaffari S. (2024). Single-layer resonant metasurfaces as versatile IR sensors, polarizers, filters, and reflectors. SPIE 13048, Radar Sensor Technology XXVIII, 1304804. https://doi.org/10.1117/12.3021205
- Upchurch-Ange K.C., Oter G., Gimlin S., Wawro Weidanz D., Weidanz J. (2023). Characterization of a novel therapeutic antibody targeting peptide/HLA-E. The Journal of Immunology, 210(Supplement 1), 146.02. https://doi.org/10.4049/jimmunol.210.Supp.146.02
- Ghaffari S., Upchurch-Ange K., Gimlin S., Tripathi T., Sluijter M., Middelburg J., van Hall T., Weidanz J. (2022). A Single-Domain TCR-like Antibody Selective for the Qa-1b/Qdm Peptide Complex Enhances Tumoricidal Activity of NK Cells via Blocking the NKG2A Immune Checkpoint. The Journal of Immunology, 208(9), 2246–2255. https://doi.org/10.4049/jimmunol.2100790
- Abdallah M.G., Buchanan-Vega J.A., Lee K.J., Wenner B.R., Allen J.W., Allen M.S., Gimlin S., Wawro Weidanz D., Magnusson R. (2020). Quantification of Neuropeptide Y with Picomolar Sensitivity Enabled by Guided-Mode Resonance Biosensors. Sensors, 20(1), 126. https://doi.org/10.3390/s20010126
- Abdallah M.G., et al. (2021). Attachment and Detection of Biofouling Yeast Cells Using Biofunctionalized Resonant Sensor Modality. IEEE Sensors Journal, 21(5), 5995–6002. https://doi.org/10.1109/JSEN.2020.3040710
- Kaja S., Hilgenberg J.D., Collins J.L., Shah A.A., Koulen P., Wawro D.D., Zimmerman S., Magnusson R.(2012). Detection of novel biomarkers for ovarian cancer with an optical nanotechnology detection system enabling label-free diagnostics. Journal of Biomedical Optics, 17(8), 081412. https://doi.org/10.1117/1.JBO.17.8.081412
- Magnusson R., Wawro D., Zimmerman S., Ding Y. (2011). Resonant Photonic Biosensors with Polarization-Based Multiparametric Discrimination in Each Channel. Sensors, 11(2), 1476–1488. https://doi.org/10.3390/s110201476
- Wawro D.D., Tibuleac S., Magnusson R., Liu H. (2000). Optical fiber endface biosensor based on resonances in dielectric waveguide gratings. In Biomedical Diagnostic, Guidance, and Surgical-Assist Systems II, SPIE, San Jose, CA, 86–94.
- Tibuleac S., Wawro D., Magnusson R. (1999). Resonant diffractive structures integrating waveguide-gratings on optical fiber endfaces. Proceedings of the 1999 IEEE LEOS Annual Meeting, San Francisco, CA.
- Magnusson R., Wang S.S. (1992). New principle for optical filters. Applied Physics Letters, 61, 1022–1024.4.
